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Casirivimab/imdevimab - Regeneron Pharmaceuticals/Roche

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Drug Profile

Casirivimab/imdevimab - Regeneron Pharmaceuticals/Roche

Alternative Names: Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies - Regeneron Pharmaceuticals/Roche; Casirivimab and Imdevimab - Regeneron Pharmaceuticals/Roche; Casirivimab+Imdevimab - Regeneron Pharmaceuticals/Roche; REGEN-COV; REGEN-COV2; REGEN-COVTM; REGN COV2; REGN-10933+ REGN-10987; REGN10933-10987; RG 6413/RG 6412; Ronapreve; SARS-CoV-2 virus multi-antibody therapy - Regeneron Pharmaceuticals/Roche

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Regeneron Pharmaceuticals
  • Developer Chugai Pharmaceutical; Regeneron Pharmaceuticals; Roche; University of Oxford
  • Class Antibodies; Antivirals; Monoclonal antibodies
  • Mechanism of Action Virus internalisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered COVID 2019 infections

Most Recent Events

  • 03 Nov 2023 Pharmacokinetics data from a phase I/II/III trial in COVID-2019 infections presented at the 2023 American College of Clinical Pharmacology Annual Meeting (ACCP-2023).
  • 10 Sep 2023 Pharmacokinetics data from a phase III trial in COVID-2019 infections presented in 2023 American College of Clinical Pharmacology Annual Meeting (ACCP-2023)
  • 18 Jun 2023 Regeneron Pharmaceuticals terminates a phase I/II trial in COVID-2019 infections (Monotherapy, Combination therapy, In adolescents, In adults) in USA (SC) due to sponsor decision (NCT05081388)
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