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CDX 527

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Drug Profile

CDX 527

Alternative Names: CDX-527

Latest Information Update: 26 Jun 2023

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At a glance

  • Originator Celldex Therapeutics Inc
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Programmed cell death-1 ligand-1 inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 06 Apr 2023 Celldex Therapeutics competes a phase-I clinical trials in Solid tumours (Metastatic disease, Late-stage disease, Second-line therapy or greater) in USA (Parenteral, Infusion) (NCT04440943)
  • 09 Nov 2022 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Parenteral)
  • 04 Jun 2021 Adverse events, pharmacokinetics and pharmacodynamics data from phase I trial in Solid tumours released by Celldex Therapeutics

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