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AGENT 797

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Drug Profile

AGENT 797

Alternative Names: AGENT-797; Allogeneic iNKT cell therapies - Agenus; Unmodified iNKT cell therapies - Agenus

Latest Information Update: 26 Nov 2025

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At a glance

  • Originator Agenus
  • Developer Agenus; MiNK Therapeutics
  • Class Antineoplastics; Antivirals; Immunotherapies; Natural killer cell therapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Adenocarcinoma; Solid tumours
  • Phase I/II SARS-CoV-2 acute respiratory disease
  • Phase I Graft-versus-host disease; Multiple myeloma

Most Recent Events

  • 13 Nov 2025 MiNK Therapeutics in collaboration with University of Wisconsin Carbone Cancer Center–Madison plans a phase 1 trial for Graft-versus-host-disease (Prevention) in USA in first quarter of 2026
  • 07 Nov 2025 Efficacy, adverse event and immunogenicity data from phase I trial in Solid tumours released by MiNK Therapeutics
  • 15 Jul 2025 Phase-I development in Multiple-myeloma (Second-line therapy or greater) is ongoing in USA (IV, Infusion) (MiNK Therapeutics pipeline; July 2025)

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