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AGENT 797

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Drug Profile

AGENT 797

Alternative Names: AGENT-797; Allogeneic iNKT cell therapies - Agenus; Unmodified iNKT cell therapies - Agenus

Latest Information Update: 27 Aug 2026

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At a glance

  • Originator Agenus
  • Developer Agenus; MiNK Therapeutics; Scripps Health
  • Class Antineoplastics; Antivirals; Immunotherapies; Natural killer cell therapies; NKT cell therapies
  • Mechanism of Action Immunologic cytotoxicity; Natural killer T-cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Acute lung injury; Adenocarcinoma; Colorectal cancer; Pneumonia; Respiratory insufficiency; Solid tumours
  • Phase I/II SARS-CoV-2 acute respiratory disease
  • Phase I Graft-versus-host disease; Multiple myeloma

Most Recent Events

  • 11 Aug 2026 MiNK Therapeutics plans a phase I trial for Graft-versus-host-disease (Prevention) in USA in October 2026 (NCT07758218)
  • 06 Aug 2026 Efficacy, adverse events and antimicrobial data from a phase II trial in Pneumonia released by MiNK Therapeutics
  • 10 Jun 2026 Phase-II clinical trials in Colorectal cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT07550088)

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