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MCARH 171

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Drug Profile

MCARH 171

Alternative Names: Autologous EGFRt/BCMA-41BBz CAR T cell therapy - Juno Therapeutics; B-cell maturation antigen-targeted EGFRt/BCMA-41BBz CAR-modified T cells; EGFRt/BCMA-41BBz CAR T cell; ET 140; MCARH171

Latest Information Update: 21 Jan 2021

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At a glance

  • Originator Memorial Sloan-Kettering Cancer Center
  • Developer Juno Therapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Epidermal growth factor receptor expression stimulants; Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Multiple myeloma

Most Recent Events

  • 20 Jan 2021 Phase-II clinical trials in Multiple myeloma (IV) (Eureka Therapeutics pipeline, January 2021)
  • 15 May 2020 MCARH 171 is still in phase I trials for Multiple myeloma in USA (NCT03070327)

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