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Zapnometinib - Atriva Therapeutics

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Drug Profile

Zapnometinib - Atriva Therapeutics

Alternative Names: ATR-002; PD01842649

Latest Information Update: 28 Feb 2026

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At a glance

  • Originator University of Muenster
  • Developer Atriva Therapeutics
  • Class Amines; Antivirals; Benzoic acids; Chlorobenzenes; Fluorobenzenes; Iodobenzenes; Small molecules
  • Mechanism of Action Mitogen-activated protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hantavirus infections
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II COVID 2019 infections
  • No development reported Hantavirus infections; Influenza virus infections

Most Recent Events

  • 28 Feb 2026 No recent reports of development identified for preclinical development in Hantavirus-infections in Germany (PO)
  • 06 Jun 2024 Atriva Therapeutics has patent protection for zapnometinib in USA
  • 04 Oct 2023 Efficacy and adverse events data from the phase IIa RESPIRE trial in COVID-2019 infections released by Atriva Therapeutics

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