Drug Profile

XmAb 819

Alternative Names: ENPP3 x CD3 - Xencor; XmAb 30819; XmAb-819

Latest Information Update: 28 Jul 2025

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At a glance

Originator Xencor
Class Antineoplastics; Bispecific antibodies; Immunotherapies
Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

No development reported Renal cancer

Most Recent Events

28 Jul 2025 No recent reports of development identified for phase-I development in Renal-cancer(Second-line therapy or greater) in USA (IV)
09 Sep 2024 Efficacy and adverse events data from a phase I trial in Renal cancer released by Xencor
27 Jun 2022 Phase-I clinical trials in Renal cancer (Second-line therapy or greater) in USA (IV) (NCT05433142)

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