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Oxybutynin/reboxetine combination therapy - Apnimed

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Drug Profile

Oxybutynin/reboxetine combination therapy - Apnimed

Alternative Names: AD-128; Reboxetine/oxybutynin - Apnimed

Latest Information Update: 28 Jun 2024

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At a glance

  • Originator Apnimed
  • Developer Apnimed; Centre Hospitalier Universitaire Vaudois; Flinders University
  • Class Alkynes; Antidepressants; Antispasmodics; Carbocyclic acids; Cyclohexanes; Diethylamines; Esters; Mandelic acids; Morpholines; Sleep disorder therapies; Small molecules
  • Mechanism of Action Adrenergic uptake inhibitors; Cholinergic receptor antagonists; Muscarinic receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II/III Sleep apnoea syndrome

Most Recent Events

  • 28 Jun 2024 No recent reports of development identified for preclinical development in Sleep-apnoea-syndrome in USA (PO, Capsule)
  • 19 Jul 2021 Centre Hospitalier Universitaire Vaudois and Apnimed complete the phase II/III OXYREB trial in Sleep apnoea syndrome in Switzerland (PO) (NCT04394143)
  • 03 Dec 2020 Apnimed and Flinders University complete a phase II trial in Sleep apnoea syndrome in Australia (PO) (ACTRN12620000662965)

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