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IDE 397

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Drug Profile

IDE 397

Alternative Names: GSK-4362676; IDE-397

Latest Information Update: 18 Mar 2026

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At a glance

  • Originator IDEAYA Biosciences
  • Developer Amgen; IDEAYA Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action MAT2A protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Bladder cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer
  • Phase I/II Solid tumours; Urogenital cancer

Most Recent Events

  • 09 Mar 2026 Pharmacodynamics data form preclinical trial in solid tumours released by IDEAYA Biosciences
  • 17 Feb 2026 IDEAYA Biosciences plans to initiate a clinical trial for Solid tumours (Combination therapy) in the second quarter of 2026 (PO)
  • 30 Jan 2026 IDEAYA Biosciences has worldwide patent protection for IDE 397

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