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IDE 397

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Drug Profile

IDE 397

Alternative Names: GSK-4362676; IDE-397

Latest Information Update: 15 Aug 2024

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At a glance

  • Originator IDEAYA Biosciences
  • Developer Amgen; IDEAYA Biosciences
  • Class Antineoplastics; Small molecules
  • Mechanism of Action MAT2A protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Bladder cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 15 Aug 2024 Phase-I development is still ongoing for Solid tumours (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in Germany (PO), prior to August 2024 (NCT04794699)
  • 15 Aug 2024 Phase-I development is still ongoing for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater, Combination therapy) in Germany (PO), prior to August 2024 (NCT04794699)
  • 06 Aug 2024 IDEAYA Biosciences announces registrational plan for Solid tumours in 2025 (PO)

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