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NIB 102

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Drug Profile

NIB 102

Alternative Names: NIB-102; TAK-102

Latest Information Update: 08 Dec 2025

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At a glance

  • Originator Yamaguchi University
  • Developer Noile-Immune Biotech; Takeda
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 08 Dec 2025 NIB 102 is still in phase-I development for Solid-tumours (In the elderly, Second-line therapy or greater, In adults) in Japan (IV, Infusion) (Noile-Immune Biotech pipeline, December 2025)
  • 28 Oct 2025 No recent reports of development identified for phase-I development in Solid-tumours(In the elderly, Second-line therapy or greater, In adults) in Japan (IV, Infusion)
  • 09 May 2025 Takeda terminates a phase-I trial in Solid-tumours (In the elderly, Second-line therapy or greater, In adults) in Japan (IV, Infusion) due to business decision unrelated to patient safety(NCT04405778)

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