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SAR 446309

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Drug Profile

SAR 446309

Alternative Names: AMX-818; HER2-XPAT - Amunix; SAR-446309; VIR-5818

Latest Information Update: 16 Jan 2025

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At a glance

  • Originator Amunix
  • Class Antineoplastics; Immunotherapies; Peptides; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 08 Jan 2025 Efficacy and adverse events data from phase-I/II trial in Solid tumours released by Vir Biotechnology
  • 31 Dec 2024 Discontinued - Phase-I/II for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease) in Spain, France, Portugal, Australia (IV)
  • 31 Dec 2024 Discontinued - Phase-I/II for Solid tumours (Late-stage disease, Metastatic disease, Monotherapy) in Australia, Portugal, Spain, France (IV)

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