INCB 106385
Alternative Names: INCB-106385Latest Information Update: 23 Jun 2025
At a glance
- Originator Incyte Corporation
- Class Antineoplastics; Small molecules
- Mechanism of Action Adenosine A2A receptor antagonists; Adenosine A2B receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Solid tumours
Most Recent Events
- 22 Feb 2024 Incyte Corporation completes a phase I trial in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Belgium, France, Italy, Spain, United Kingdom and the US (PO) (NCT04580485)
- 02 May 2023 Discontinued - Phase-I for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) prior to May 2023
- 02 May 2023 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (PO) prior to May 2023