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GC 008T

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Drug Profile

GC 008T

Alternative Names: CRISPR-engineered CAR-T cells - Gracell Biotechnology; GC008t; Mesothelin-directed CAR-T cells - Gracell Biotechnology

Latest Information Update: 26 Feb 2024

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At a glance

  • Originator Gracell Biotechnology
  • Developer Chinese PLA General Hospital; Gracell Biotechnology
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 22 Feb 2024 Gracell Biotechnology has been acquired by AstraZeneca
  • 28 Jan 2022 No recent reports of development identified for phase-I development in Solid-tumours(In the elderly, Late-stage disease, Second-line therapy or greater, In adults) in China (Parenteral, Infusion)
  • 29 May 2020 Efficacy, adverse events and pharmacokinetics data from a phase I trial in Solid tumours presented at the 56th Annual Meeting of the American Society of Clinical Oncology (ASCO-2020)

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