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PA 317

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Drug Profile

PA 317

Alternative Names: Anti-CD7 chimeric antigen receptor T- cell therapy - PersonGen Biomedicine; Autologous CD7-CAR-T cells - PersonGen Biotherapeutics; CD7-CAR-T cells - PersonGen Biotherapeutics; PA3-17

Latest Information Update: 23 Sep 2025

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At a glance

  • Originator PersonGen Biotherapeutics
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor T-cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Phase II T-cell lymphoma
  • Phase I Precursor T-cell lymphoblastic leukaemia-lymphoma
  • No development reported Lymphoid leukaemia

Most Recent Events

  • 17 Sep 2025 NMPA approves IND application for a pivotal phase II clinical trial in patients with relapsed/refractory T-lymphoblastic leukemia/lymphoma (R/R T-ALL/LBL)
  • 17 Sep 2025 PersonGen Biomedicine plans a phase II trial for relapsed/refractory T-lymphoblastic leukemia/lymphoma
  • 24 Jun 2025 Efficacy data from a phase-I trial in Precursor B-cell lymphoblastic leukaemia-lymphoma released by PersonGen Biotherapeutics

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