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TAK 280

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Drug Profile

TAK 280

Alternative Names: B7H3 x CD3 COBRA; MVC 280; TAK-280

Latest Information Update: 14 Jul 2024

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At a glance

  • Originator Maverick Therapeutics
  • Developer Takeda
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action CD3 antigen stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Solid tumours

Most Recent Events

  • 22 Apr 2022 Phase-I/II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA, Spain, Canada (IV) (NCT05220098)
  • 22 Apr 2022 Phase-I/II clinical trials in Solid tumours (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Australia (IV) (NCT05220098)
  • 03 Jun 2020 Maveric Therapeutics plans a phase I/II trial for MVC 280 in Solid tumours (Parenteral) in second half of 2021 (Maveric Therapeutics pipeline, June 2020)

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