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Imatinib inhalation - Aerami Therapeutics

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Drug Profile

Imatinib inhalation - Aerami Therapeutics

Alternative Names: AER-901; Inhaled imatinib - Aerami Therapeutics; VR-325

Latest Information Update: 10 Oct 2023

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At a glance

  • Originator Vectura
  • Developer Aerami Therapeutics
  • Class Amines; Anti-inflammatories; Antineoplastics; Antivirals; Benzamides; Eye disorder therapies; Piperazines; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Bcr-abl tyrosine kinase inhibitors; Platelet derived growth factor alpha receptor antagonists; Platelet-derived growth factor receptor antagonists; Proto oncogene protein c-kit inhibitors; Signal transduction pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension
  • New Molecular Entity No

Highest Development Phases

  • Phase I Pulmonary arterial hypertension; Pulmonary hypertension

Most Recent Events

  • 30 Sep 2023 Aerami Therapeutics updated an open IND application with the US FDA for a phase II proof-of-concept trial in Pulmonary arterial hypertension
  • 12 Sep 2023 Adverse events and pharmacokinetics data from a phase-I trial in Pulmonary arterial hypertension presented at the International Congress of European Respiratory Society (ERS-2023)
  • 12 Sep 2023 Aerami Therapeutics plans phase-II uniPHied trial for pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease (Inhalation)
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