Drug Profile

Vepafestinib - Helsinn/Taiho Pharmaceutical

Alternative Names: HM-06; TAS-0953

Latest Information Update: 12 Jan 2024

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At a glance

Originator Helsinn; Taiho Pharmaceutical
Class Antineoplastics
Mechanism of Action Proto-oncogene protein c-ret inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I/II Solid tumours
Preclinical Brain metastases; Non-small cell lung cancer

Most Recent Events

12 Jan 2024 3843454- Preclinical data with KDM and HE. Phase I/II trial is already updated
11 Oct 2023 Pharmacodynamics data from a preclinical studies in cancer presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2023 (AACR-NCI-EORTC-2023)
14 Aug 2023 Chemical structure information added

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