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ONC 212

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Drug Profile

ONC 212

Alternative Names: ONC-212

Latest Information Update: 20 Jun 2025

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At a glance

  • Originator Oncoceutics
  • Developer Chimerix; Oncoceutics
  • Class 3-ring heterocyclic compounds; Antineoplastics; Fluorobenzenes; Imidazoles; Pyrimidines; Small molecules
  • Mechanism of Action Apoptosis stimulants; Endopeptidase Clp stimulants; G protein-coupled receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Adenocarcinoma; Biliary cancer; Ewing's sarcoma; Glioma; Liver cancer; Pancreatic cancer
  • No development reported Acute myeloid leukaemia

Most Recent Events

  • 20 Jun 2025 Pharmacodynamics data from preclinical trial in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics and pharmacokinetics data from a preclinical studies in Biliary tract cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 25 Apr 2025 Pharmacodynamics data from preclinical trial in Cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)

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