Drug Profile

Sodium oxybate once-nightly - Jazz Pharmaceuticals plc

Alternative Names: JZP-324

Latest Information Update: 28 Feb 2026

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At a glance

Originator Jazz Pharmaceuticals plc
Class Butyric acids; Hydroxybutyrates; Sleep disorder therapies; Small molecules
Mechanism of Action Dopamine receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

28 Feb 2026 No recent reports of development identified for phase-I development in Narcolepsy(In volunteers) in Ireland (PO)
26 Feb 2024 Sodium oxybate is still in phase I trial for Narcolepsy (In volunteers) in Ireland (PO) (Jazz Pharmaceuticals plc Pipeline, February 2024)
28 Oct 2023 No recent reports of development identified for phase-I development in Narcolepsy(In volunteers) in Ireland (PO)

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