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DUET 01

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Drug Profile

DUET 01

Alternative Names: CO-sTiRNA; CpG STAT3siRNA - City of Hope National Medical Center/Scopus BioPharma; CpG-STAT3siRNA; CpG-STAT3siRNA gene therapy - City of Hope; DUET-01

Latest Information Update: 28 Feb 2025

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At a glance

  • Originator City of Hope National Medical Center
  • Developer Scopus BioPharma
  • Class Antineoplastics; Gene therapies; Immunotherapies
  • Mechanism of Action RNA interference; STAT3 transcription factor inhibitors; Toll-like receptor 9 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Cutaneous T-cell lymphoma; Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 28 Feb 2025 No recent reports of development identified for preclinical development in Cutaneous-T-cell-lymphoma(Combination therapy) in USA (Intratumoural, Injection)
  • 28 Feb 2025 No recent reports of development identified for preclinical development in Non-Hodgkin's-lymphoma(Combination therapy) in USA (Intratumoural, Injection)
  • 28 Oct 2024 No recent reports of development identified for phase-I development in Non-Hodgkin's-lymphoma in USA (Intratumoural, Injection)

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