Obrixtamig - Boehringer Ingelheim
Alternative Names: BI-764532; DLL3/CD3 T-cell engager - Boehringer Ingelheim; OBT-620Latest Information Update: 04 Jun 2025
At a glance
- Originator Boehringer Ingelheim
- Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
- Mechanism of Action Cytotoxic T lymphocyte stimulants; Immunologic cytotoxicity
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Neuroendocrine tumours; Small cell lung cancer
- Phase I Glioma
Most Recent Events
- 22 May 2025 Updated efficacy and adverse events data from a phase I trial in Small cell lung cancer and Neuroendocrine tumours released by Boehringer Ingelheim
- 13 Sep 2024 Updated efficacy and adverse events data from a phase I trial in Small cell lung cancer and Neuroendocrine tumours presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
- 07 Sep 2024 Updated efficacy and adverse event data from a phase I trial in Neuroendocrine tumours and Small cell lung cancer presented at the 25th World Conference on Lung Cancer (WCLC-2024)