Drug Profile

RZ 402

Alternative Names: AB-402; ASP 440; RZ-402

Latest Information Update: 22 Aug 2024

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At a glance

Originator ActiveSite Pharmaceuticals
Developer Rezolute
Class Amides; Amidines; Anti-inflammatories; Eye disorder therapies; Pyrazoles; Small molecules
Mechanism of Action Kallikrein inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Phase II Diabetic macular oedema
Discontinued Diabetic retinopathy

Most Recent Events

22 Aug 2024 RZ 402 is available for licensing as of 13 Aug 2024
21 May 2024 Adverse events and efficacy data from phase II trial in Diabetic macular edema released by Rezolute
13 Dec 2023 Rezolute completes enrolment in its phase II trial in Diabetic macular oedema in USA (PO) (NCT05712720)

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