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IMA 401

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Drug Profile

IMA 401

Alternative Names: IMA-401; IMA401 MAGEA4/8; IMA401 TCER™; MAGE A4/8 TCER

Latest Information Update: 22 Jul 2026

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At a glance

  • Originator immatics biotechnologies GmbH
  • Developer Immatics N.V.
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Non-small cell lung cancer; Solid tumours

Most Recent Events

  • 02 Jun 2026 Efficacy and adverse events data from a phase I trial in Solid tumors presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)
  • 31 May 2026 Phase-I clinical trials in Non small cell lung cancer (Combination therapy) (IV)
  • 31 May 2026 Efficacy and adverse events data from a phase Ia/Ib trial in Solid tumours released by Immatics

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