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IMA 401

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Drug Profile

IMA 401

Alternative Names: IMA-401; IMA401 TCER™; MAGE A4/8 TCER

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator immatics biotechnologies GmbH
  • Developer Immatics N.V.
  • Class Antineoplastics; Immunoglobulin fragments; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in Germany (IV)
  • 31 Dec 2024 IMA 401 is no longer licensed to Bristol-Myers Squibb
  • 17 Sep 2024 Efficacy, adverse events and pharmacokinetic data from a phase I trial in Solid tumours released by Immatics

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