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SGR 2921

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Drug Profile

SGR 2921

Alternative Names: CDC7 program; SDGR1 program - Schrodinger; SDGR1-CDC7; SDR 3066; SGR-2921

Latest Information Update: 10 Mar 2025

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At a glance

  • Originator Schrodinger
  • Class Antineoplastics; Small molecules
  • Mechanism of Action CDC7 protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Myelodysplastic syndromes
  • No development reported Colorectal cancer; Non-small cell lung cancer; Oesophageal cancer

Most Recent Events

  • 31 Jan 2025 SGR 2921 receives Orphan Drug status for Acute myeloid leukaemia in USA
  • 13 Jan 2025 SGR 2921 receives Fast Track designation for Acute myeloid leukaemia [PO] (Monotherapy, Second-line therapy or greater) in USA before January 2025
  • 28 Jul 2024 No recent reports of development identified for preclinical development in Non-small-cell-lung-cancer in USA

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