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SOS1/KRAS protein-protein interaction inhibitor - Schrodinger/Bristol Myers Squibb

Drug Profile

SOS1/KRAS protein-protein interaction inhibitor - Schrodinger/Bristol Myers Squibb

Alternative Names: SDGR5 program - Schrodinger; SDGR5-SOS1 / KRAS

Latest Information Update: 13 Feb 2025

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At a glance

  • Originator Schrodinger
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Protein-protein interaction inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 13 Feb 2025 Phase-I clinical trials in Solid tumours in USA (unspecified route) (Bristol Myers Squibb pipeline, February 2025)
  • 10 Sep 2024 Preclinical trials in Cancer in USA (unspecified route) prior to September 2024 (Schrodinger pipeline, September 2024)
  • 13 May 2020 Schrodinger intends to initiate IND-enabling studies by the first half of 2021

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