SOS1/KRAS protein-protein interaction inhibitor - Schrodinger/Bristol Myers Squibb
Alternative Names: SDGR5 program - Schrodinger; SDGR5-SOS1 / KRASLatest Information Update: 13 Feb 2025
At a glance
- Originator Schrodinger
- Class Antineoplastics; Small molecules
- Mechanism of Action Protein-protein interaction inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 13 Feb 2025 Phase-I clinical trials in Solid tumours in USA (unspecified route) (Bristol Myers Squibb pipeline, February 2025)
- 10 Sep 2024 Preclinical trials in Cancer in USA (unspecified route) prior to September 2024 (Schrodinger pipeline, September 2024)
- 13 May 2020 Schrodinger intends to initiate IND-enabling studies by the first half of 2021