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JPX 1188

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Drug Profile

JPX 1188

Alternative Names: JPX-1188

Latest Information Update: 11 Apr 2022

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At a glance

  • Originator Janpix
  • Developer Centessa Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action STAT3 transcription factor inhibitors; STAT5 transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; T-cell prolymphocytic leukaemia

Most Recent Events

  • 04 Apr 2022 Discontinued - Preclinical for Acute myeloid leukaemia in Canada (Parenteral) (Centessa pipeline, April 2022)
  • 04 Apr 2022 Discontinued - Preclinical for T-cell prolymphocytic leukaemia in Canada (Parenteral) (Centessa pipeline, April 2022)
  • 16 Feb 2021 Janpix has merged with Centessa Pharmaceuticals to form Centessa Pharmaceuticals

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