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Sevasemten - Edgewise Therapeutics

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Drug Profile

Sevasemten - Edgewise Therapeutics

Alternative Names: EDG-5506

Latest Information Update: 08 Jun 2026

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At a glance

  • Originator Edgewise Therapeutics
  • Class Ethers; Fluorinated hydrocarbons; Ketones; Pyridazines; Pyridines; Pyrimidines; Small molecules
  • Mechanism of Action Creatine kinase inhibitors; Myosin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Duchenne muscular dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Duchenne muscular dystrophy
  • Phase II Glycogen storage disease type V; Limb girdle muscular dystrophies

Most Recent Events

  • 01 Jun 2026 Servier acquires Sevasemtem from Edgewise Therapeutics
  • 10 Mar 2026 Efficacy data from the phase II MESA trial in Duchenne muscular dystrophy released by Edgewise Therapeutics
  • 13 Jan 2026 Edgewise Therapeutics plans the NDA submission of Becker muscular dystrophy to the US FDA in the first half of 2027

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