Drug Profile

CD25 x CTLA-4 bispecific DART molecule - MacroGenics

Alternative Names: CD25 x CTLA-4 bispecific DART® molecule - MacroGenics; CD25 x CTLA-4 DART Molecule - MacroGenics

Latest Information Update: 28 Jul 2024

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At a glance

Originator MacroGenics
Class Antineoplastics; Immunotherapies; Recombinant fusion proteins
Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants; Cytotoxic T-lymphocyte antigen 4 inhibitors; Regulatory T-lymphocyte inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

28 Jul 2024 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)
22 Jun 2020 Preclinical trials in Cancer in USA (Parenteral) before June 2020
22 Jun 2020 Pharmacodynamics data from preclinical studies in Cancer released by MacroGenics

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