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VTP 300

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Drug Profile

VTP 300

Alternative Names: ChAdOx1-HBV; Chimpanzee adenovirus-vectored hepatitis B virus vaccine - Barinthus Biotherapeutics; VTP-300

Latest Information Update: 23 Oct 2025

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At a glance

  • Originator University of Oxford
  • Developer Arbutus Biopharma; Barinthus Biotherapeutics
  • Class Hepatitis B vaccines; Synthetic vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Hepatitis B

Most Recent Events

  • 07 May 2025 Immunogenicity and adverse event data from a phase IIa trial in Hepatitis B presented at the European Association for the Study of the Liver Congress 2025
  • 07 May 2025 Efficacy and adverse events data from a phase II HBV003 trial in Hepatitis B presented at the European Association for the Study of the Liver Congress 2025 (EASL-2025)
  • 07 May 2025 Efficacy data from the phase IIa IM-PROVE II trial in Chronic hepatitis B infection released by Barinthus Biotherapeutics

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