Nelistotug - GSK
Alternative Names: GSK-6097608; GSK’608; GSK’608 CD96Latest Information Update: 28 Nov 2025
At a glance
- Originator GlaxoSmithKline
- Developer 23andMe; GSK
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; CD96 antigen inhibitors; T lymphocyte replacements
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Non-small cell lung cancer; Solid tumours; Squamous cell cancer
Most Recent Events
- 29 Oct 2025 Discontinued - Phase-I for Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, Recurrent, Second-line therapy or greater) in Japan, Canada, South Korea, USA (IV) (GSK pipeline, October 2025)
- 29 Oct 2025 Discontinued - Phase-I for Solid tumours (Late-stage disease, Metastatic disease, Monotherapy, Recurrent, Second-line therapy or greater) in USA, Japan, South Korea, Canada (IV) (GSK pipeline, October 2025)
- 29 Oct 2025 Discontinued - Phase-II for Non-small cell lung cancer (Combination therapy, Late-stage disease, Second-line therapy or greater) in USA, Canada, France, Germany, Italy, Russia, Netherlands, Romania, Spain, South Korea, Poland, Sweden (Parenteral) (GSK pipeline, October 2025)