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Trastuzumab rezetecan - Jiangsu HengRui Medicine Co

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Drug Profile

Trastuzumab rezetecan - Jiangsu HengRui Medicine Co

Alternative Names: A1811; SHR-1811; SHR-A1811

Latest Information Update: 16 Feb 2026

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Fudan University; Jiangsu Hengrui Medicine Co.; Suzhou Suncadia Biopharmaceuticals
  • Class Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Non-small cell lung cancer
  • Phase III Adenocarcinoma; Breast cancer; Colorectal cancer; HER2 positive breast cancer; Ovarian cancer; Triple negative breast cancer
  • Phase II Biliary cancer; Cervical cancer; Gynaecological cancer; Salivary gland cancer; Urogenital cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 06 Feb 2026 Shanghai Jiao Tong University initiates enrolment in a phase II trial for Breast cancer (First line therapy, Neoadjuvant therapy, Combination therapy) in China (NCT07393425)
  • 02 Feb 2026 Launched for Non-small cell lung cancer (Second-line therapy or greater, Metastatic disease, Inoperable/Unresectable, Late-stage disease) in China (IV), prior to February 2026 (Jiangsu HengRui Medicine pipeline, February 2026)
  • 30 Dec 2025 Peking Union Medical College Hospital plans a phase II trial for Colorectal cancer (Metastatic disease, Combination-therapy, Recurrent, Second-line therapy or greater) (Parenteral, Injection) (NCT07355764)

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