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Trastuzumab rezetecan - Jiangsu HengRui Medicine Co

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Drug Profile

Trastuzumab rezetecan - Jiangsu HengRui Medicine Co

Alternative Names: SHR-A1811

Latest Information Update: 16 Dec 2025

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Fudan University; Jiangsu Hengrui Medicine Co.; Suzhou Suncadia Biopharmaceuticals
  • Class Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Non-small cell lung cancer
  • Phase III Adenocarcinoma; Breast cancer; Colorectal cancer; HER2 positive breast cancer; Ovarian cancer
  • Phase II Biliary cancer; Cervical cancer; Gynaecological cancer; Salivary gland cancer; Urogenital cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 01 Dec 2025 Suzhou Suncadia Biopharmaceuticals plans a phase I trial for Solid tumours in China (SC) (NCT07275242)
  • 27 Nov 2025 Phase-II clinical trials in Urogenital cancer (Late-stage disease, Metastatic disease, Combination therapy) in China (IV) (NCT07241793)
  • 23 Oct 2025 Phase-III clinical trials in HER2-positive-breast-cancer (Neoadjuvant therapy) in China (Parenteral) (NCT07196774)

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