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Trastuzumab rezetecan - Jiangsu HengRui Medicine Co

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Drug Profile

Trastuzumab rezetecan - Jiangsu HengRui Medicine Co

Alternative Names: SHR-A1811

Latest Information Update: 22 Sep 2025

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At a glance

  • Originator Jiangsu Hengrui Medicine Co.
  • Developer Fudan University; Jiangsu Hengrui Medicine Co.; Suzhou Suncadia Biopharmaceuticals
  • Class Antineoplastics; Camptothecins; Drug conjugates; Immunoconjugates; Monoclonal antibodies
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Non-small cell lung cancer
  • Phase III Adenocarcinoma; Breast cancer; Colorectal cancer; HER2 positive breast cancer; Ovarian cancer
  • Phase II Biliary cancer; Gynaecological cancer; Salivary gland cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 17 Sep 2025 Peking University Cancer Hospital & Institute plans a phase I/II trial for HER2-positive Breast Cancer (Late stage disease) (IV, infusion) in September 2025 (NCT07177950)
  • 10 Sep 2025 Jiangsu HengRui Medicine plans a phase II trial for HER2-positive Breast Cancer (Late-stage disease, Inoperable/Unresectable, Metastatic disease, Combination therapy, First-line therapy) in China (IV) (NCT07179939)
  • 26 Aug 2025 Jiangsu HengRui Medicine plans a phase II trial for HER2-positive Breast Cancer (Neoadjuvant Therapy, In adults, In the elderly) in China (NCT07129187)

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