HIX 763
Alternative Names: HIX-763Latest Information Update: 21 Feb 2025
At a glance
- Originator Intellia Therapeutics
- Developer Novartis
- Class Antianaemics; Gene therapies; Haematopoietic stem cells therapies; Stem cell therapies
- Mechanism of Action Cell replacements; Fetal haemoglobin expression stimulants
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Discontinued Sickle cell anaemia
Most Recent Events
- 11 Feb 2025 Novartis terminates a phase I/II trial in Sickle cell anaemia (In children, In adolescents, In adults) in USA (IV), due to the decision of early termination was made due to business reasons and was not a consequence of any safety concern (NCT04443907)
- 23 Feb 2023 Discontinued - Phase-I/II for Sickle cell anaemia (In adolescents, In children, In adults) in USA (IV)
- 01 Mar 2022 Caribou Biosciences has patents pending for next-generation CRISPR genome editing technology worldwide