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Divarasib - Genentech

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Drug Profile

Divarasib - Genentech

Alternative Names: GDC-6036; RG 6330; RO-7435846

Latest Information Update: 20 Dec 2024

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At a glance

  • Originator Genentech
  • Developer Genentech; Roche
  • Class Aminopyridines; Antineoplastics; Chlorinated hydrocarbons; Fluorine compounds; Ketones; Piperazines; Pyrrolidines; Quinazolines; Small molecules
  • Mechanism of Action KRAS protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Non-small cell lung cancer
  • Phase I Breast cancer; Solid tumours

Most Recent Events

  • 16 Dec 2024 Genentech plans a phase I pharmacokinetics trial (In volunteers) (PO) in December 2024 (NCT06734208)
  • 15 Nov 2024 Genentech initiates enrolment in a phase I trial in healthy volunteers in the US (PO) (NCT06690138)
  • 15 Nov 2024 Genentech plans a phase I trial (In volunteers) in the US (PO) (NCT06690138, GP45714)

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