Drug Profile

HTL 0048149

Alternative Names: GPR52 agonist - Nxera Pharma; HTL'149; HTL-0048149; HTL-A; NXE-0048149; pEC50 7.5

Latest Information Update: 02 Apr 2024

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At a glance

Originator Sosei Heptares
Developer Nxera Pharma
Class Antipsychotics; Neuroprotectants; Small molecules
Mechanism of Action G protein-coupled receptor agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase I Schizophrenia

Most Recent Events

31 Mar 2024 Sosei Heptares is now called Nxera Pharma
11 Mar 2024 Boehringer Ingelheim in-licenses HTL 0048149 from Sosei Heptares
11 Mar 2024 Sosei Heptares plans a phase Ib trial for Schizophrenia

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