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Ateganosine - MAIA Biotechnology

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Drug Profile

Ateganosine - MAIA Biotechnology

Alternative Names: 2'-Deoxythioguanosine; 6-thio-2’-deoxyguanosine - MAIA Biotechnology; 6-thio-dG - MAIA Biotechnology; THIO - MAIA Biotechnology

Latest Information Update: 15 Dec 2025

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At a glance

  • Originator MAIA Biotechnology
  • Class Amines; Antineoplastics; Deoxyribonucleosides; Purines; Small molecules; Thiones
  • Mechanism of Action Cell death stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer; Small cell lung cancer; Glioblastoma
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase III Non-small cell lung cancer
  • Preclinical Glioma; Liver cancer; Small cell lung cancer

Most Recent Events

  • 21 Nov 2025 Phase-III clinical trials in Non-small cell lung cancer (Late-stage disease, Combination therapy, Second-line therapy or greater, Metastatic disease) (IV) before November 2025 (NCT06908304) (CTIS2024-520164-33-00)
  • 11 Sep 2025 Efficacy data from the phase II THIO-101 trial in Non-small cell lung cancer released by MAIA Biotechnology
  • 13 Aug 2025 MAIA Biotechnology has 10 patent protection for Ateganosine worldwide including Europe (validated in 19 countries) .

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