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2 Deoxythioguanosine - MAIA Biotechnology

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Drug Profile

2 Deoxythioguanosine - MAIA Biotechnology

Alternative Names: 2'-Deoxythioguanosine; 6-thio-2’-deoxyguanosine - MAIA Biotechnology; 6-thio-dG - MAIA Biotechnology; THIO - MAIA Biotechnology

Latest Information Update: 15 Sep 2024

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At a glance

  • Originator MAIA Biotechnology
  • Class Amines; Antineoplastics; Deoxyribonucleosides; Purines; Small molecules; Thiones
  • Mechanism of Action Cell death stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer; Small cell lung cancer; Glioblastoma
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Preclinical Glioma; Liver cancer; Small cell lung cancer

Most Recent Events

  • 10 Sep 2024 Updated efficacy data from the phase II THIO-101 trial in Non-small cell lung cancer released by MAIA Biotechnology
  • 04 Jun 2024 Updated efficacy data from a phase II THIO-101 trial in Non-small cell lung cancer released by MAIA Biotechnology
  • 31 May 2024 Efficacy and adverse events data from a phase II trial in Non small cell lung cancer presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)

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