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CMTX 101

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Drug Profile

CMTX 101

Alternative Names: CMTX-001; CMTX-101

Latest Information Update: 19 Jun 2025

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At a glance

  • Originator Clarametyx Biosciences
  • Class Anti-inflammatories; Antibacterials; Monoclonal antibodies
  • Mechanism of Action Bacterial biofilm inhibitors; DNA-binding protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Pseudomonal infections
  • Phase I Community-acquired pneumonia
  • No development reported Nosocomial pneumonia; Otitis media

Most Recent Events

  • 16 Jun 2025 Interim adverse events and efficacy data from a phase Ib/IIa trial in Pseudomonal infections released by Clarametyx Biosciences
  • 21 Oct 2024 Clarametyx Biosciences terminates phase I trial in Community-acquired pneumonia (In volunteers) in USA (IV), due to slow enrollment and no safety issues were identified (NCT05629741)
  • 28 Aug 2024 No recent reports of development identified for preclinical development in Nosocomial-pneumonia in USA (Parenteral)

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