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Istisociclib - Concentra Biosciences

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Drug Profile

Istisociclib - Concentra Biosciences

Alternative Names: KB-0742; KI-ARv-03

Latest Information Update: 28 Aug 2025

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At a glance

  • Originator Kronos Bio
  • Class Antineoplastics; Cyclopentanes; Diamines; Pyrazolones; Pyrimidines; Small molecules
  • Mechanism of Action Cyclin-dependent kinase 9 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 24 Dec 2024 Chemical structure information added.
  • 13 Nov 2024 Discontinued - Phase-I/II for Non-Hodgkin's lymphoma (In adolescents, In children, In the elderly, Second-line therapy or greater, In adults) in USA, Spain, United Kingdom (PO)
  • 13 Nov 2024 Discontinued - Phase-I/II for Solid tumours (In adolescents, In children, In the elderly, Second-line therapy or greater, In adults) in USA, Spain, United Kingdom (PO)

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