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TQS 168

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Drug Profile

TQS 168

Alternative Names: T-168; TQS-168

Latest Information Update: 08 Aug 2025

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At a glance

  • Originator Tranquis Therapeutics
  • Developer Endurance Bio; Tranquis Therapeutics
  • Class Anti-inflammatories; Antidementias; Small molecules
  • Mechanism of Action Myeloid cell modulators; Peroxisome proliferator-activated receptor modulators; TFEB protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyotrophic lateral sclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Parkinson's disease
  • Phase I Amyotrophic lateral sclerosis
  • Preclinical Neurodegenerative disorders

Most Recent Events

  • 22 May 2025 Phase-II clinical trials in Parkinson's disease in Norway (PO) (Endurance Bio pipeline August 2025)
  • 22 May 2025 Endurance Bio plans the phase IIb/III SLEIPNIR trial for Parkinson’s disease (PO)
  • 30 Apr 2025 Endurance Bio acquires T 168 from Tranquis Therapeutics (Endurance Bio pipeline, July 2025)

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