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KT 474

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Drug Profile

KT 474

Alternative Names: KT-474; SAR-444656

Latest Information Update: 06 Nov 2024

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At a glance

  • Originator Kymera Therapeutics
  • Developer Kymera Therapeutics; Sanofi
  • Class Anti-inflammatories; Antirheumatics; Skin disorder therapies; Small molecules
  • Mechanism of Action Interleukin-1 receptor-associated kinase degraders
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atopic dermatitis; Hidradenitis suppurativa
  • Preclinical Multiple sclerosis
  • No development reported Autoimmune disorders; Rheumatoid arthritis

Most Recent Events

  • 31 Oct 2024 Kymera Therapeutics plans a phase III registrational trial for Hidradenitis suppurativa (HS) and Atopic dermatitis
  • 28 Aug 2024 No recent reports of development identified for preclinical development in Autoimmune-disorders in France (PO)
  • 28 Aug 2024 No recent reports of development identified for preclinical development in Rheumatoid-arthritis in France (PO)

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