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Research programme: anti-CD3/anti-MSLN bispecific antibody constructs - Amgen

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Drug Profile

Research programme: anti-CD3/anti-MSLN bispecific antibody constructs - Amgen

Alternative Names: Anti-MSLN/CD3 BiTE® antibody; MSLN HLE BiTE®

Latest Information Update: 28 Jul 2022

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At a glance

  • Originator Amgen
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Recombinant fusion proteins
  • Mechanism of Action T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 Jul 2022 No recent reports of development identified for preclinical development in Solid-tumours in USA (IV)
  • 22 Jun 2020 anti-CD3/anti-MSLN bispecific antibody constructs are still in preclinical trials for Solid tumours in USA
  • 22 Jun 2020 Pharmacodynamics data from a preclinical trial in Solid tumours presented at the 111th Annual Meeting of the American Association for Cancer Research - II (AACR-2020)

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