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Lasmotinib - Pharos iBio

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Drug Profile

Lasmotinib - Pharos iBio

Alternative Names: PHI-101

Latest Information Update: 31 Jan 2026

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At a glance

  • Originator Pharos I&BT Co
  • Developer Pharos iBio; Seoul National University Hospital
  • Class Alkynes; Amides; Antineoplastics; Fluorobenzenes; Piperidines; Small molecules; Thiophenes; Urea compounds
  • Mechanism of Action Checkpoint kinase 2 inhibitors; Fms-like tyrosine kinase 3 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Acute myeloid leukaemia; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Preclinical Triple negative breast cancer

Most Recent Events

  • 31 Jan 2026 Chemical structure information added.
  • 24 Dec 2025 Lasmotinib - Pharos iBio receives Orphan Drug status for Acute myeloid leukaemia in European Union
  • 24 Dec 2025 Lasmotinib - Pharos iBio receives Orphan Drug status for Acute myeloid leukaemia in South Korea

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