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BTX 1188

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Drug Profile

BTX 1188

Alternative Names: BTX 1188; BTX-508

Latest Information Update: 03 Oct 2023

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At a glance

  • Originator Hebrew University of Jerusalem
  • Developer BioTheryX
  • Class Antineoplastics; Small molecules
  • Mechanism of Action CRBN protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Myelodysplastic syndromes; Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 26 Sep 2023 Discontinued - Phase-I/II for Acute myeloid leukaemia (Late-stage disease, Second-line therapy or greater) in USA (PO) (BioTheryx pipeline, September 2023)
  • 26 Sep 2023 Discontinued - Phase-I/II for Non-Hodgkin's lymphoma (Late-stage disease, Second-line therapy or greater) in USA (PO) (BioTheryx pipeline, September 2023)
  • 26 Sep 2023 Discontinued - Phase-I/II for Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (BioTheryx pipeline, September 2023)

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