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BMS 986340

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Drug Profile

BMS 986340

Alternative Names: anti-CCR8 - Bristol-Myers Squibb; BMS-986340; ONO-7427

Latest Information Update: 28 Jan 2025

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Bristol-Myers Squibb; Ono Pharmaceutical
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CCR8 receptor antagonists; Regulatory T-lymphocyte inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours

Most Recent Events

  • 23 Jan 2025 Phase-II clinical trials in Solid tumours (Combination therapy) in Japan (Parenteral), (Ono Pharmaceutical pipeline, January 2025)
  • 27 May 2021 Phase-I/II clinical trials in Solid tumours (Late-stage disease, Second-line therapy or greater, Metastatic disease, Combination therapy) in USA (Parenteral) (NCT04895709)
  • 21 May 2021 Bristol-Myers Squibb plans a first-in-human phase I/II trial for Solid tumours (Monotherapy, Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA in May 2021 (NCT04895709) (EudraCT2021-001188-26)

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