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PMR 116

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Drug Profile

PMR 116

Alternative Names: PMR-116

Latest Information Update: 24 Jun 2024

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At a glance

  • Originator Pimera
  • Class Antineoplastics; Small molecules
  • Mechanism of Action RNA polymerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Acute myeloid leukaemia; B-cell lymphoma; Liver cancer; Precursor B-cell lymphoblastic leukaemia-lymphoma; Prostate cancer; Sarcoma

Most Recent Events

  • 24 Jun 2024 PMR 116 is still in phase-I trial in Solid-tumours(Late-stage disease) in Australia (PO, Liquid) (ACTRN12620001146987)
  • 05 Apr 2024 Pharmacodynamics data from preclinical studies in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research(AACR-2024)
  • 28 Dec 2023 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in Australia (PO, Liquid)

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