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AD 214

Drug Profile

AD 214

Alternative Names: AD-214; i-body based therapeutics - AdAlta

Latest Information Update: 22 Feb 2024

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At a glance

  • Originator AdAlta
  • Developer AdAlta; The Alfred Hospital
  • Class Antifibrotics; Eye disorder therapies; Immunoglobulin Fc fragments; Recombinant fusion proteins
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis; Interstitial lung diseases; Renal failure
  • Preclinical Wet age-related macular degeneration

Most Recent Events

  • 09 Feb 2024 AdAlta completes a phase-I clinical trials in Renal failure in Australia (IV) (NCT05914909)
  • 10 Aug 2023 Phase-I clinical trials in Renal failure in Australia (IV) (NCT05914909)
  • 10 Aug 2023 AdAlta initiates enrolment in a phase I extension trial for Interstitial lung disease or Chronic kidney disease in Australia
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