Ebrasodebart - Enthera
Alternative Names: ENT-001Latest Information Update: 26 Sep 2025
At a glance
- Originator Ospedale San Raffaele
- Developer Enthera
- Class Anti-inflammatories; Antihyperglycaemics; Monoclonal antibodies
- Mechanism of Action Insulin like growth factor binding protein 3 inhibitors; TMEM219 protein inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I Inflammatory bowel diseases; Type 1 diabetes mellitus
Most Recent Events
- 26 Sep 2025 Ebrasodebart is still in phase I trials for Inflammatory bowel disease and Type 1 diabetes mellitus (In Volunteers) in Netherlands (IV, Infusion)
- 15 Sep 2025 Pharmacodynamics data from a preclinical trial in type 1 diabetes presented at the 61st Annual Meeting of the European Association for the Study of Diabetes (EASD-2025)
- 28 May 2025 Pharmacodynamics data from a preclinical trial in Inflammatory bowel diseases released by Enthera