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HBI 2376

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Drug Profile

HBI 2376

Alternative Names: GH-21; HBI-2376

Latest Information Update: 28 Jan 2025

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At a glance

  • Originator Suzhou Genhouse Bio
  • Developer HUYA Bioscience International; Suzhou Genhouse Bio
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Protein tyrosine phosphatase non-receptor type 11 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • Phase I/II Non-small cell lung cancer

Most Recent Events

  • 28 Jan 2025 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO)
  • 31 May 2024 Suzhou Genhouse Bio in collaboration with Zhejiang Cancer Hospital plans a phase I/II trial for Solid tumors (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in July 2024 (NCT06435455)
  • 28 Apr 2024 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease) in China (PO, Capsule)

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