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REGN 5381

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Drug Profile

REGN 5381

Alternative Names: REGN-5381

Latest Information Update: 23 Jun 2025

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At a glance

  • Originator Regeneron Pharmaceuticals
  • Class Heart failure therapies; Immunoglobulins; Natriuretic agents; Recombinant proteins
  • Mechanism of Action Atrial natriuretic factor receptor A agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Heart failure; Hypertension

Most Recent Events

  • 02 Jun 2025 Regeneron Pharmaceuticals completes a phase II trial in Heart failure (In adults, In the elderly) in Moldova (IV) (NCT05353166)
  • 16 Apr 2025 Phase-II clinical trials in Hypertension (Treatment-experienced) in United Kingdom (IV) (NCT06833190)
  • 18 Feb 2025 Regeneron Pharmaceuticals plans a phase II trial for Hypertension (Treatment experienced) (Parenteral) in April 2025 (NCT06833190)

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