Drug Profile

REGN 5381

Alternative Names: REGN-5381

Latest Information Update: 02 Dec 2025

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At a glance

Originator Regeneron Pharmaceuticals
Class Heart failure therapies; Immunoglobulins; Natriuretic agents; Recombinant proteins
Mechanism of Action Atrial natriuretic factor receptor A agonists

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes
Available For Licensing Yes

Highest Development Phases

Discontinued Heart failure; Hypertension

Most Recent Events

02 Dec 2025 Discontinued - Phase-I for Heart failure (In volunteers) in Germany (IV)
02 Dec 2025 Discontinued - Phase-II for Heart failure in Belgium (IV)
02 Dec 2025 Discontinued - Phase-II for Heart failure in Bulgaria (IV)

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